Regioselective silylation of pyranosides using a boronic acid/Lewis base co-catalyst system.
نویسندگان
چکیده
The combination of a boronic acid and a Lewis base, both employed in substoichiometric amounts, enables the regioselective silylation of cis-diol groups in alkylpyranoside substrates. The proposed mode of activation involves the formation of a tetracoordinate adduct that displays enhanced nucleophilicity at the boron-bound alkoxide groups.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 33 شماره
صفحات -
تاریخ انتشار 2013